Author's response to reviews Title: Polymorphism in COX-2 modifies the inverse association between Helicobacter pylori seropositivity and esophageal squamous cell carcinoma risk in Taiwan: a case control study Authors:

Polymorphism in COX-2 modifies the inverse association between Helicobacter pylori seropositivity and esophageal squamous cell carcinoma risk in Taiwan: a case control study

BACKGROUND Overexpression of Cyclooxygenase-2 (COX-2) was observed in many types of cancers, including esophageal squamous cell carcinoma (ESCC). One functional SNP, COX-2 -1195G/A, has been reported to mediate susceptibility of ESCC in Chinese populations. In our previous study, the presence of Helicobacter pylori (H. pylori) was found to play a protective role in development of ESCC. The inte...

Author's response to reviews Title: Macronutrients, vitamins and minerals intake and risk of esophageal squamous cell carcinoma: a case-control study in Iran Authors:

Author's response to reviews Title: Diet Folate, DNA Methylation and Genetic Polymorphisms of MTHFR C677T in Association with the Prognosis of Esophageal Squamous Cell Carcinoma Authors:

Association between XRCC1 (rs1799782) Gene Polymorphism and Oral squamous cell carcinoma

Background and purpose: Oral squamous cell carcinoma (OSCC) is the most common tumor of the head and neck. XRCC1 is a DNA repair gene and there are controversies about the association between XRCC1 gene polymorphism (RS1799782) in pathogenesis and susceptibility to OSCC. The purpose of this study was to investigate the association between XRCC1 (rs1799782) gene polymorphism and its dominant all...

Serum pepsinogens and Helicobacter pylori are not associated with esophageal squamous cell carcinoma in a high-risk area in China.

AIMS AND BACKGROUND The role of serum pepsinogen level and Helicobacter pylori infection in esophageal carcinoma remains controversial. It may be a risk or protective factor, or without association with esophageal carcinoma. We prospectively examined associations between serum pepsinogen status, H pylori infection and the risk of esophageal squamous cell carcinoma in the Chinese population. M...